Gray scored 19 of her game-high 32 points in the first half as the Bears (14-5, 6-2 Pac-12) opened a 37-31 halftime lead, then let her teammates do the scoring during a 13-2 run midway through the second half that put the decision away.
Gray got the run started with a layup before Brittany Boyd took over, scoring seven points during the spurt.
Gray also had 15 rebounds for the Golden Bears, while Boyd had 18 points, six assists and three steals.
Nirra Fields paced the Bruins (10-11, 4-5) with 26 points and 10 rebounds. Thea Lemberger had four assists and Corinne Costa blocked six shots.
UCLA was 21-for-56 (37.5 percent) overall, 3-for-11 (27.3 percent) from 3-point land and 8-for-15 (53.3 percent) from theline. Cal was 24-for-53 (45.3 percent), 1-for-9 (11.1 percent) and 20-for-24 (83.3 percent).
The Golden Bears dominated the boards 43-28 and committed 19 turnovers to 17 for the Bruins.
It’s rivalry weekend for Cal as they open a home-and-home weekend against Stanford at Maples Pavilion on Thursday night at 8 p.m.